If someone were to ask you where the hope for the future of antibiotic drugs was going to come from, your answer probably would be anything besides ‘soil’.
On the other hand, you may also have known that some extremely dangerous bacteria (such as those associated with the disease tetanus) are also found in this substance; therefore, it may be reasonable to assume that some soil-living micro-organisms may have evolved chemical defences against others.
The Simple Blood Test for Alzheimer’s is Nearly Here: Researchers Prove Their Plasma Analysis is Comparable to Diagnostic Standard
Alzheimer’s disease (AD) is one of the most prominent and well-known progressive neurodegenerative conditions that affect humanity.
It is a form of dementia related to excessive levels of proteins such as tau and amyloid-beta in certain brain regions. Treatment for AD is gradually becoming more and more effective; with many more patients capable of living more or less normal lives while managing their conditions over time.
The risk of developing many different forms of cancer may be strongly associated with age. Some scientists even agree that there may be a “power law” that connects increasing age to increasing susceptibilities to cancer. However, a new study, conducted at Dundee University, disrupts this theory with evidence of a new statistical link between thymic functions and the age-related risk of cancer. This new data may be the basis of a new, immune system-based hypothesis to be used in the study and treatment of relevant diseases.
Leprosy, caused by Mycobacterium leprae has been around since time immemorial, or in fact the Iron Age, to be exact.
Although curable with MDT (multidrug therapy) in the early stages, the disease severely affects the lungs, skin and eyes, and in extreme cases, results in disability. There are more than 200,000 cases of leprosy reported, every year, in countries of South America and Asia.
Experts are trying to gain insights into the bacteria’s drug-resistant strains, its origin and evolution, which could lead to the elimination of the disease in the long-run.
The resistance to antibiotic medications is an ever-more prominent public health issue. This phenomenon is related to the acquisition of novel properties or adaptations that allow bacteria to avoid death caused by these drugs.
Type 1 diabetes is an autoimmune condition in which the patient’s ability to produce insulin is negated by their body’s own protective processes, often from an early age. As with type 2 diabetes, it can require chronic medical treatment from the point of diagnosis in order to avoid severe, even life-threatening, disease events.
The first cases of Ebola virus disease (EVD) were registered in Africa’s Sudan and Congo, and since then it has spread by contamination and human-to-human transmission to several parts of West Africa and surrounding regions.
Hailing from the Filoviridae family, the disease is incurable and, most often, fatal.
According to the Global Burden of Skin Disease, skin conditions were ranked fourth in leading causes of disability, globally, and was the 18th leading cause of DALYs (disability-adjusted life year).
Another serious condition sweeping nations is melanoma, a type of skin cancer affecting more than 85,000 individuals per year in the US alone.
The management of type 1 diabetes mellitus is an extensive, cumbersome process for patients as it involves rigid schedules and maintenance with regard to administering insulin injections regularly.
As of 2017, according to the National Diabetes Statistics Report, more than 30 million people around the world are suffering with diabetes, a tenth of that affecting the American population.
Obesity is a serious public health problem that is taking hold of the vast majority of countries in the developed world. For example, approximately 4 of every 10 adults in America is obese.
Obesity may have a considerable negative impact on quality of life, as it can impede normal independent movement and exercise. It may also lead to chronic health problems such as cardiovascular disease, type 2 diabetes and non-alcoholic liver failure.
We all know that a diet containing a lot of salt can be bad for us, leading to high blood pressure and cardiovascular disease. Despite this, an estimated 90 percent of Americans eat more than the recommended amount of 2300 mg per day.
Now, new research suggests that the harmful effects of too much salt could be worse than we originally thought.
Melanoma is the most severe form of skin cancer. It can even be fatal, although timely detection and treatment can effectively protect against this eventuality. This treatment may come in the form of surgical incision, or as medical anti-tumour therapy.
Medical treatment for melanoma has resulted in full remission for some patients. However, adaptations in these tumours have led to relapses for others. This is true for a recently-developed treatment called anti-PD-1 therapy.
Whilst most of us know that we need to take action and make changes to our livelihoods in order to reduce our impact on the environment, it’s sometimes hard to know where to start.
Actions such as reducing our carbon footprint through flying less is a great place to start, but if you only plan on taking an overseas holiday once a year, sometimes you might feel like you need to do more on a daily basis in order to make more of a difference.
Newly released research suggests that the memory loss and brain degeneration commonly associated with Alzheimer’s disease might just be helped using a drug primarily developed for the treatment of diabetes.
Beta-lactams are a class of antibiotic medications that enjoyed an initial run of efficacy against their bacterial targets. They do so by disrupting the process by which bacteria form protective cellular walls around themselves, thus killing individual units and preventing their multiplication within a host’s tissues. Examples of beta-lactams include carbapenems, cephalosporins and the classic antibiotic penicillin.
As of 2017, more than 5 million Americans are living with Alzheimer’s, and the numbers are predicted to rise to 16 million in the next 30 years or so.
As this disease is a neurodegenerative form of dementia, including memory loss and behavioral changes, scientists around the world are trying to study components of the brain and different parts of the body in order to better understand its origin.
Although affecting less than one million people in the United States, junctional epidermolysis bullosa (JEB) is a lethal genetic condition that causes severe blistering and erosions on the skin by means of injury or from friction by scratching. Those who survive endure chronic wounds that can often lead to skin cancer, and sometimes even death.
A new trial funded by Diabetes UK has found that dramatic changes in the diets of people suffering from type 2 diabetes can actually reverse their symptoms, even for patients who had been diagnosed with the disease up to six years previously.
Today, there are many projects that investigate new and emerging treatments that address a critical factor in cancer progression: the tumor microenvironment. This is a complex process, in which cancer cells adjust the conditions within, and also possibly in the immediate vicinity of, the tumor they have formed to their own ‘liking’. Tumors develop their own internal environments for a number of reasons, which include resistance to aspects of the patient’s immune system which could be capable of destroying or damaging them otherwise.
It is accepted by many that a higher bodyweight (measured by body-mass index or BMI) increases the risk of disease and death. However, recent research trends have suggested that this relationship is not as simple as once thought. This may be related to observational associations between increasing BMI and mortality, which may lead to conclusions that a slightly higher BMI is actually protective against death. However, other researchers assert that this is not a causal relationship, mainly because it does not account for other factors such as lifestyle choices and illnesses at their onset.